The “Genomic Code”: DNA Pervasively Moulds Chromatin Structures Leaving no Room for “Junk”

The chromatin of the human genome was analyzed at three DNA size levels. At the first, compartment level, two “gene spaces” were found many years ago: A GC-rich, gene-rich “genome core” and a GC-poor, gene-poor “genome desert”, the former corresponding to open chromatin centrally located in the inte...

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Bibliographic Details
Main Author: Giorgio Bernardi
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/11/4/342