An Efficient, Self-Protecting Route to Dimethyl 4-Amino-4-[2-(methoxycarbonyl)ethyl]-heptanedioate HCl

A method to reduce the nitro moiety in dimethyl 4-nitro-4-[1-[2(methoxycarbonyl)ethyl]]heptanedioate using a T-1 Raney nickel catalyst in an acidic environment is reported. The method avoids facile lactam formation.

Bibliographic Details
Main Authors: Rita S. K. Majerle, Sally Henrie
Format: Article
Language:English
Published: MDPI AG 1999-02-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/4/1/13/