Mitochondrial Regulation of Macrophage Response Against Pathogens

Mitochondrial Regulation of Macrophage Response Against Pathogens

Innate immune cells play the first line of defense against pathogens. Phagocytosis or invasion by pathogens can affect mitochondrial metabolism in macrophages by diverse mechanisms and shape the macrophage response (proinflammatory vs. immunomodulatory) against pathogens. Besides β-nicotinamide aden...

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Bibliographic Details
Main Authors: Subhadip Choudhuri, Imran Hussain Chowdhury, Nisha Jain Garg
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
mitochondria
metabolism
macrophage
innate immunity
cGAS-STING
mitophagy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.622602/full

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