When Cells Suffocate: Autophagy in Cancer and Immune Cells under Low Oxygen

Hypoxia is a signature feature of growing tumors. This cellular state creates an inhospitable condition that impedes the growth and function of all cells within the immediate and surrounding tumor microenvironment. To adapt to hypoxia, cells activate autophagy and undergo a metabolic shift increasin...

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Bibliographic Details
Main Authors: Katrin Schlie, Jaeline E. Spowart, Luke R. K. Hughson, Katelin N. Townsend, Julian J. Lum
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:International Journal of Cell Biology
Online Access:http://dx.doi.org/10.1155/2011/470597