The long march: a sample preparation technique that enhances contig length and coverage by high-throughput short-read sequencing.

The long march: a sample preparation technique that enhances contig length and coverage by high-throughput short-read sequencing.

High-throughput short-read technologies have revolutionized DNA sequencing by drastically reducing the cost per base of sequencing information. Despite producing gigabases of sequence per run, these technologies still present obstacles in resequencing and de novo assembly applications due to biased...

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Bibliographic Details
Main Authors: Katherine Sorber, Charles Chiu, Dale Webster, Michelle Dimon, J Graham Ruby, Armin Hekele, Joseph L DeRisi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2566813?pdf=render

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