Evaluation of the systemic toxicity and mutagenicity of OLIGOPIN®, procyanidolic oligomers (OPC) extracted from French Maritime Pine Bark extract
The potential systemic toxicity of Oligopin®, a French Maritime Pine Bark extract (FMPBE) rich in procyanidolic oligomers, was evaluated in an acute oral limit test and a 90-day repeated dose oral toxicity study with Sprague Dawley rats. The potential mutagenicity was assessed in a bacterial reverse...
Main Authors: | L Segal, MG Penman, Y Piriou |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-01-01
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Series: | Toxicology Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2214750018301914 |
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