Role of sinoatrial node architecture in maintaining a balanced source-sink relationship and synchronous cardiac pacemaking

Role of sinoatrial node architecture in maintaining a balanced source-sink relationship and synchronous cardiac pacemaking

Normal heart rhythm (sinus rhythm) depends on regular activity of the sinoatrial node (SAN), a heterogeneous collection of specialized myocytes in the right atrium. SAN cells, in general, possess a unique electrophysiological profile that promotes spontaneous electrical activity (automaticity). How...

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Bibliographic Details
Main Authors:	Sathya D Unudurthi, Roseanne M Wolf, Thomas eHund
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2014-11-01
Series:	Frontiers in Physiology
Subjects:	Sick Sinus Syndrome Sinoatrial Node arrhythmia electrical coupling automaticity pacemaking
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00446/full

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