Colorectal advanced neoplasms occur through dual carcinogenesis pathways in individuals with coexisting serrated polyps.

Colorectal advanced neoplasms occur through dual carcinogenesis pathways in individuals with coexisting serrated polyps.

Individuals with serrated polyps (SP) are at higher risk for synchronous colorectal advanced neoplasms (AN) and cancers. However, it remains unclear whether there is a unique involvement of the serrated pathway and/or the classical adenoma-carcinoma sequence in this setting.Colorectal ANs, which inc...

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Bibliographic Details
Main Authors: Atsushi Yamada, Sachiko Minamiguchi, Yoshiharu Sakai, Takahiro Horimatsu, Manabu Muto, Tsutomu Chiba, C Richard Boland, Ajay Goel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4029807?pdf=render

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