The Role of Angiogenesis in Human Non-Hodgkin Lymphomas
The role of angiogenesis in the growth of lymphomas and survival of patients with leukemias and other hematological malignancies has become evident since 1994. Angiogenic factors, such as vascular endothelial growth factor and its receptors together with other tumor microenvironment components, inc...
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2013-03-01
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Series: | Neoplasia: An International Journal for Oncology Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S147655861380053X |
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doaj-e37935be562a46e78d0de80555fe9af52020-11-25T00:55:21ZengElsevierNeoplasia: An International Journal for Oncology Research1476-55861522-80022013-03-0115323123810.1593/neo.121962The Role of Angiogenesis in Human Non-Hodgkin LymphomasDomenico Ribatti0Beatrice Nico1Girolamo Ranieri2Giorgina Specchia3Angelo Vacca4Department of Basic Medical Sciences, Neurosciences and Sensory Organs, Section of Human Anatomy and Histology, University of Bari Medical School, Bari, ItalyDepartment of Basic Medical Sciences, Neurosciences and Sensory Organs, Section of Human Anatomy and Histology, University of Bari Medical School, Bari, ItalyNational Cancer Institute “Giovanni Paolo II”, Bari, ItalyDepartment of Emergency and Transplantation, Hematology Section, University of Bari Medical School, Bari, ItalyDepartment of Internal Medicine and Clinical Oncology, University of Bari Medical School, Bari, Italy The role of angiogenesis in the growth of lymphomas and survival of patients with leukemias and other hematological malignancies has become evident since 1994. Angiogenic factors, such as vascular endothelial growth factor and its receptors together with other tumor microenvironment components, including myelo-monocytic cell, mast cells, endothelial progenitor cells, and circulating endothelial cells, have been shown to be important in the progression and maintenance of lymphoproliferative disorders. In this review article, we present an overview of the literature focusing on the relationship between angiogenesis and disease progression and the recent advantages in the antiangiogenic treatment in human non-Hodgkin lymphomas. http://www.sciencedirect.com/science/article/pii/S147655861380053X |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Domenico Ribatti Beatrice Nico Girolamo Ranieri Giorgina Specchia Angelo Vacca |
spellingShingle |
Domenico Ribatti Beatrice Nico Girolamo Ranieri Giorgina Specchia Angelo Vacca The Role of Angiogenesis in Human Non-Hodgkin Lymphomas Neoplasia: An International Journal for Oncology Research |
author_facet |
Domenico Ribatti Beatrice Nico Girolamo Ranieri Giorgina Specchia Angelo Vacca |
author_sort |
Domenico Ribatti |
title |
The Role of Angiogenesis in Human Non-Hodgkin Lymphomas |
title_short |
The Role of Angiogenesis in Human Non-Hodgkin Lymphomas |
title_full |
The Role of Angiogenesis in Human Non-Hodgkin Lymphomas |
title_fullStr |
The Role of Angiogenesis in Human Non-Hodgkin Lymphomas |
title_full_unstemmed |
The Role of Angiogenesis in Human Non-Hodgkin Lymphomas |
title_sort |
role of angiogenesis in human non-hodgkin lymphomas |
publisher |
Elsevier |
series |
Neoplasia: An International Journal for Oncology Research |
issn |
1476-5586 1522-8002 |
publishDate |
2013-03-01 |
description |
The role of angiogenesis in the growth of lymphomas and survival of patients with leukemias and other hematological malignancies has become evident since 1994. Angiogenic factors, such as vascular endothelial growth factor and its receptors together with other tumor microenvironment components, including myelo-monocytic cell, mast cells, endothelial progenitor cells, and circulating endothelial cells, have been shown to be important in the progression and maintenance of lymphoproliferative disorders. In this review article, we present an overview of the literature focusing on the relationship between angiogenesis and disease progression and the recent advantages in the antiangiogenic treatment in human non-Hodgkin lymphomas.
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url |
http://www.sciencedirect.com/science/article/pii/S147655861380053X |
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