Glial pathology and retinal neurotoxicity in the anterior visual pathway in experimental autoimmune encephalomyelitis

Glial pathology and retinal neurotoxicity in the anterior visual pathway in experimental autoimmune encephalomyelitis

Abstract The animal model experimental autoimmune encephalomyelitis (EAE) has been used extensively in the past to test mechanisms that target peripheral immune cells for treatment of multiple sclerosis (MS). While there have been some notable successes in relapsing MS, the development of therapies...

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Bibliographic Details
Main Authors: Jing Jin, Matthew D. Smith, Calvin J. Kersbergen, Tae-In Kam, Mayuri Viswanathan, Kyle Martin, Ted M. Dawson, Valina L. Dawson, Donald J. Zack, Katharine Whartenby, Peter A. Calabresi
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Acta Neuropathologica Communications
Subjects:
EAE
Astrocytes
Retinal ganglion cells
Optic neuritis
Online Access:http://link.springer.com/article/10.1186/s40478-019-0767-6

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