Abnormal Innate Immunity in Acute-on-Chronic Liver Failure: Immunotargets for Therapeutics

Abnormal Innate Immunity in Acute-on-Chronic Liver Failure: Immunotargets for Therapeutics

Acute-on-chronic liver failure (ACLF) is a severe life-threatening condition with high risk of multiorgan failure, sepsis, and mortality. ACLF activates a multifaceted interplay of both innate and adaptive immune response in the host which governs the overall outcome. Innate immune cells recognize t...

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Bibliographic Details
Main Authors: Arshi Khanam, Shyam Kottilil
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Immunology
Subjects:
acute-on-chronic liver failure
innate immune cells
cytokines
liver damage
immune targets
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.02013/full

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