Identification of key regulators responsible for dysregulated networks in osteoarthritis by large-scale expression analysis

Identification of key regulators responsible for dysregulated networks in osteoarthritis by large-scale expression analysis

Abstract Background Osteoarthritis (OA) is a worldwide musculoskeletal disorder. However, disease-modifying therapies for OA are not available. Here, we aimed to characterize the molecular signatures of OA and to identify novel therapeutic targets and strategies to improve the treatment of OA. Metho...

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Bibliographic Details
Main Authors: Song Shi, Fuyin Wan, Zhenyu Zhou, Ran Tao, Yue Lu, Ming Zhou, Fan Liu, Yake Liu
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Osteoarthritis
Transcriptional profiling
Drug repurposing
Online Access:https://doi.org/10.1186/s13018-021-02402-9

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