Functional and mechanistic studies reveal MAGEA3 as a pro-survival factor in pancreatic cancer cells

Functional and mechanistic studies reveal MAGEA3 as a pro-survival factor in pancreatic cancer cells

Abstract Background In the era of personalized therapy, functional annotation of less frequent genetic aberrations will be instrumental in adapting effective therapeutic in clinic. Overexpression of Melanoma associated antigen A3 (MAGEA3) is reported in certain pancreatic cancer (PCA) patients. The...

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Bibliographic Details
Main Authors: Biswajit Das, Shantibhusan Senapati
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
MAGEA3
Pancreatic cancer
CCL2
Survivin
Autophagy
Cancer testis antigen
Online Access:http://link.springer.com/article/10.1186/s13046-019-1272-2

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