Transcriptomic Analysis of the Chicken MDA5 Response Genes
RIG-I and MDA5 are two key pattern recognition receptors that sense RNA virus invasion, but RIG-I is absent in chickens. Although chickens have intact MDA5, the genes downstream of chicken MDA5 (chMDA5) that may mediate antiviral response are not well studied. We compared the transcriptional profile...
Main Authors: | Shiman Yu, Haiying Mao, Meilin Jin, Xian Lin |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-03-01
|
Series: | Genes |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4425/11/3/308 |
Similar Items
-
hnRNPH2 as an Inhibitor of Chicken MDA5-Mediated Type I Interferon Response: Analysis Using Chicken MDA5–Host Interactome
by: Xian Lin, et al.
Published: (2020-10-01) -
Chicken optineurin suppresses MDA5-mediated interferon β production
by: Yu Li, et al.
Published: (2021-01-01) -
Comparative Structure and Function Analysis of the RIG-I-Like Receptors: RIG-I and MDA5
by: Morgan Brisse, et al.
Published: (2019-07-01) -
Targeted Knockout of MDA5 and TLR3 in the DF-1 Chicken Fibroblast Cell Line Impairs Innate Immune Response Against RNA Ligands
by: Su Bin Lee, et al.
Published: (2020-04-01) -
Regulatory effects of chicken TRIM25 on the replication of ALV-A and the MDA5-mediated type I interferon response
by: Jin-run Zhou, et al.
Published: (2020-12-01)