Assessing current therapeutic approaches to decode potential resistance mechanisms in glioblastomas

Assessing current therapeutic approaches to decode potential resistance mechanisms in glioblastomas

Unique astrocytic cell infiltrating growth and glial tumor growth in the confined skull make human glioblastoma multiforme (GBM) one of the most difficult cancers to treat in modern medicine. Prognosis for patients is very poor, as they die more or less within 12 months. Patients either die of the c...

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Bibliographic Details
Main Authors: Chun-I eSze, Ming-Fu eChiang, Wan-Pei eSu, Yu-An eChen, Nan-Shan eChang
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-03-01
Series:Frontiers in Oncology
Subjects:
Extracellular Matrix
Cancer stem cell
resistance mechanisms
Glioblastoma Multiforme
TIAF1 expression
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00059/full

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