Evidence for the Involvement of the Master Transcription Factor NF-κB in Cancer Initiation and Progression

Evidence for the Involvement of the Master Transcription Factor NF-κB in Cancer Initiation and Progression

Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is responsible for the regulation of a large number of genes that are involved in important physiological processes, including survival, inflammation, and immune responses. At the same time, this transcription factor can control...

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Bibliographic Details
Main Authors: Yu Rou Puar, Muthu K Shanmugam, Lu Fan, Frank Arfuso, Gautam Sethi, Vinay Tergaonkar
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Biomedicines
Subjects:
NF-κB
cancer
apoptosis
metastasis
pharmacological inhibition
Online Access:http://www.mdpi.com/2227-9059/6/3/82

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