Senescence and tumor suppression [version 1; referees: 2 approved]
Cellular senescence has emerged as a potent tumor suppression mechanism that restrains proliferation of cells at risk for malignant transformation. Although senescent cells have permanently exited the cell cycle, their presence can have detrimental effects on the surrounding tissue, largely due to t...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2017-12-01
|
Series: | F1000Research |
Subjects: | |
Online Access: | https://f1000research.com/articles/6-2121/v1 |