Lipopolysaccharide-Deficient Acinetobacter baumannii Due to Colistin Resistance Is Killed by Neutrophil-Produced Lysozyme

Lipopolysaccharide-Deficient Acinetobacter baumannii Due to Colistin Resistance Is Killed by Neutrophil-Produced Lysozyme

Acinetobacter baumannii causes nosocomial infections due to its multidrug resistance and high environmental adaptability. Colistin is a polypeptide antibacterial agent that targets lipopolysaccharide (LPS) and is currently used to control serious multidrug-resistant Gram-negative bacterial infection...

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Bibliographic Details
Main Authors: Go Kamoshida, Takuya Akaji, Norihiko Takemoto, Yusuke Suzuki, Yoshinori Sato, Daichi Kai, Taishi Hibino, Daiki Yamaguchi, Takane Kikuchi-Ueda, Satoshi Nishida, Yuka Unno, Shigeru Tansho-Nagakawa, Tsuneyuki Ubagai, Tohru Miyoshi-Akiyama, Masataka Oda, Yasuo Ono
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Microbiology
Subjects:
Acinetobacter baumannii
colistin
LPS
lysozyme
neutrophil
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.00573/full

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