Exploring the smallest active fragment of HsQSOX1b and finding a highly efficient oxidative engine.

Human quiescin-sulfhydryl oxidase 1 isoform b (HsQSOX1b) is a highly efficient, multiple-domain enzyme that directly inserts disulfide bonds into client protein. However, previous studies have focused mainly on the catalytic activity of the whole protein rather than its domain structure. In this res...

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Bibliographic Details
Main Authors: Wenyun Zheng, Wenyao Zhang, Wei Hu, Chao Zhang, Yi Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3401233?pdf=render