Dermatopathic lymphadenitis in a patient with pemphigus vulgaris

• Main Authors: Jen-Jung Cheng, Han Chang, Hung-Chun Shih, Shiow-Jiuan Wey, Yu-Ping Hsiao
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2013-06-01
• Series: Dermatologica Sinica
• Subjects: dermatopathic lymphadenitis; lepomelanotic reticulosis; mycosis fungoides; Pautrier-Woringer disease; pemphigus vulgaris; Sézary syndrome
• Online Access: http://www.sciencedirect.com/science/article/pii/S1027811712000882

Dermatopathic lymphadenitis (DL) is a reactive lymphoid hyperplasia that commonly involves the regional lymph nodes in patients with chronic dermatoses, such as exfoliative dermatitis, toxic-shock syndrome, pemphigus, psoriasis, eczema, and, in severe cases, mycosis fungoides. Diagnosis of DL depends on the histopathologic characteristics of paracortical T-zone expansion with melanin, hemosiderin, or lipid-laden macrophages. Lymphadenopathies in patients with chronic dermatoses may be due not only to infections or malignancy, but also to reactive disorders such as DL. We describe the case of a 31-year-old woman with pemphigus vulgaris who has characteristic manifestations of DL.