Histological and immunohistological aspects of the ovarian cycle of the algerian wild sand rat, Psammomys obesus Cretzschmar, 1828.

The sand rat, Psammomys obesus, is largely used as a model for studying several metabolic disorders. In order to perform breeding laboratory conditions, the reproductive function of this species was investigated. Using histological and immunohistochemical techniques, several aspects of the ovaries w...

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Bibliographic Details
Main Authors: Farida Khammar, ThĂŠrese Gernigon-Spychalowicz, Amina Boubekri, Jean-Marie Exbrayat
Format: Article
Language:English
Published: Via Medica 2008-04-01
Series:Folia Histochemica et Cytobiologica
Online Access:http://czasopisma.viamedica.pl/fhc/article/view/4487
Description
Summary:The sand rat, Psammomys obesus, is largely used as a model for studying several metabolic disorders. In order to perform breeding laboratory conditions, the reproductive function of this species was investigated. Using histological and immunohistochemical techniques, several aspects of the ovaries were studied throughout the sexual cycle. During the ovarian cycle, the different stages of folliculogenesis, from primordial to Graafian follicle, have been shown; the differentiation of both granulosa and theca cells, the formation of the antrum, cumulus oophorus and corona radiate were described. Broken follicles and corpora lutea have been observed, confirming a spontaneous ovulation in isolated females. Steroid activities were analysed using immunohistochemical techniques. Estrogen, androgen and progesterone hormones were visualized in the different compartments of the ovary.
ISSN:0239-8508
1897-5631