Microglial activation and cell death induced by the mitochondrial toxin 3-nitropropionic acid: in vitro and in vivo studies

Metabolic impairment of neurons has been implicated in several neurological disorders, but it is not at present known whether such metabolic impairment has deleterious effects on microglia, the phagocytic cells of the central nervous system (CNS). In the present study, we examined whether metabolic...

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Bibliographic Details
Main Authors: Jae K Ryu, Atsushi Nagai, Jean Kim, Min C Lee, James G McLarnon, Seung U Kim
Format: Article
Language:English
Published: Elsevier 2003-03-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996103000020