Deletion of pgi gene in E. coli increases tolerance to furfural and 5-hydroxymethyl furfural in media containing glucose–xylose mixture

Deletion of pgi gene in E. coli increases tolerance to furfural and 5-hydroxymethyl furfural in media containing glucose–xylose mixture

Abstract Background Furfural and 5-hydroxymethyl furfural (5-HMF) are key furan inhibitors that are generated due to breakdown of lignocellulosic sugars at high temperature and acidic treatment conditions. Both furfural and 5-HMF act in a synergistic manner to inhibit microbial metabolism and resist...

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Bibliographic Details
Main Authors: Syed Bilal Jilani, Chandra Dev, Danish Eqbal, Kamran Jawed, Rajendra Prasad, Syed Shams Yazdani
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Microbial Cell Factories
Subjects:
Escherichia coli
Furfural
5-hydroxymethyl furfural
Glucose
Xylose
Co-utilization
Online Access:http://link.springer.com/article/10.1186/s12934-020-01414-0

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http://link.springer.com/article/10.1186/s12934-020-01414-0

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