Early predictors of neonatal intraventricular hemorrhage
Objective: Current study aimed toward the early prediction of neonatal intraventricular hemorrhage (IVH) for better management and prognosis. Methods: This prospective study was conducted on forty neonates at the Neonatal Intensive Care Unit of Pediatrics and Medical Biochemistry department (Tant...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Electronic Physician
2017-08-01
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| Series: | Electronic Physician |
| Subjects: | |
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614277/ |
| Summary: | Objective: Current study aimed toward the early prediction of neonatal intraventricular hemorrhage (IVH) for
better management and prognosis.
Methods: This prospective study was conducted on forty neonates at the Neonatal Intensive Care Unit of
Pediatrics and Medical Biochemistry department (Tanta University, Egypt) from July 2016 to June 2017. Cord
blood erythropoietin and venous blood Activin A were assayed within the first hour of life. Neonates were
divided into 2 groups: Group 1 (with IVH) included twenty neonates who developed IVH proved by transcranial
ultrasonography (u/s) and Group 2 (without IVH) included twenty neonates who were admitted to the NICU but
did not develop IVH, also proved by transcranial u/s. Data were analyzed using Chi Square and t-test.
Results: Group 1 had a significantly higher cord blood erythropoietin concentration than group 2 (46.75±27.98
mIU/mL vs. 18.82±8.91 mIU/mL), respectively (p<0.05). Group 1 had a significantly higher venous blood
Activin A concentration than group 2 (3.18±2 ng/L vs. 0.42±0.25 ng/L) with (p<0.05).
Conclusion: Cord blood erythropoietin and venous blood Activin A were presumed to be used as early predictors
of IVH in neonates with early treatment and better prognosis |
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| ISSN: | 2008-5842 2008-5842 |