Targeting neuropilin-1 to inhibit VEGF signaling in cancer: Comparison of therapeutic approaches.

Angiogenesis (neovascularization) plays a crucial role in a variety of physiological and pathological conditions including cancer, cardiovascular disease, and wound healing. Vascular endothelial growth factor (VEGF) is a critical regulator of angiogenesis. Multiple VEGF receptors are expressed on en...

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Bibliographic Details
Main Authors: Feilim Mac Gabhann, Aleksander S Popel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-12-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC1761657?pdf=render