Targeting neuropilin-1 to inhibit VEGF signaling in cancer: Comparison of therapeutic approaches.
Angiogenesis (neovascularization) plays a crucial role in a variety of physiological and pathological conditions including cancer, cardiovascular disease, and wound healing. Vascular endothelial growth factor (VEGF) is a critical regulator of angiogenesis. Multiple VEGF receptors are expressed on en...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2006-12-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC1761657?pdf=render |