KISS1/KISS1R in Cancer: Friend or Foe?

The KISS1 gene encodes KISS1, a protein that is rapidly processed in serum into smaller but biologically active peptides called kisspeptins (KPs). KISS1 and the KPs signal via the G-protein coupled receptor KISS1R. While KISS1 and KPs are recognized as potent positive regulators of the reproductive...

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Bibliographic Details
Main Authors: Stephania Guzman, Muriel Brackstone, Sally Radovick, Andy V. Babwah, Moshmi M. Bhattacharya
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2018.00437/full