Mechanisms of Regulation of the Chemokine-Receptor Network

Mechanisms of Regulation of the Chemokine-Receptor Network

The interactions of chemokines with their G protein-coupled receptors promote the migration of leukocytes during normal immune function and as a key aspect of the inflammatory response to tissue injury or infection. This review summarizes the major cellular and biochemical mechanisms by which the in...

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Bibliographic Details
Main Authors: Martin J. Stone, Jenni A. Hayward, Cheng Huang, Zil E. Huma, Julie Sanchez
Format: Article
Language:English
Published: MDPI AG 2017-02-01
Series:International Journal of Molecular Sciences
Subjects:
chemokine
chemokine receptor
regulation
binding
expression
glycosaminoglycan
post-translational modification
oligomerization
signaling
inhibitor
Online Access:http://www.mdpi.com/1422-0067/18/2/342

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http://www.mdpi.com/1422-0067/18/2/342

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