Identification of the major metabolite of 12-HETE produced by renal tubular epithelial cells.

The identification and polarity of release of the major metabolite of 12-HETE produced by cultured canine renal tubular epithelial cells was determined. When incubated with 1.0 microM [3H]12-HETE for 1 h, cultured Madin Darby Canine Kidney (MDCK) cells converted 35% of the radiolabeled 12-HETE to a...

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Bibliographic Details
Main Authors: J A Gordon, P H Figard, A A Spector
Format: Article
Language:English
Published: Elsevier 1989-05-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520383322