Genomic alterations in gastric cancers discovered via whole-exome sequencing

Genomic alterations in gastric cancers discovered via whole-exome sequencing

Abstract Background Gastric cancer (GC) ranks the second in mortality rate among all cancers. Metastases account for most of the deaths in GC patients. Yet our understanding of GC and its metastasis mechanism is still very limited. Methods We performed 20 whole-exome sequencing (WES) on 5 typical me...

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Bibliographic Details
Main Authors: Jie Zhang, Weiqing Qiu, Hua Liu, Changlin Qian, Dujuan Liu, Hailong Wang, Ni Hu, Y. Tom Tang, Jianhua Sun, Zhiyong Shen
Format: Article
Language:English
Published: BMC 2018-12-01
Series:BMC Cancer
Subjects:
Whole-exome sequencing
Candidate mutations
Gastric adenocarcinoma (GAC)
SNP
Metastasis
Copy number variation (CNV)
Online Access:http://link.springer.com/article/10.1186/s12885-018-5097-8

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