Association between a Prognostic Gene Signature and Functional Gene Sets

Background The development of expression-based gene signatures for predicting prognosis or class membership is a popular and challenging task. Besides their stringent validation, signatures need a functional interpretation and must be placed in a biological context. Popular tools such as Gene Set En...

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Bibliographic Details
Main Authors: Manuela Hummel, Klaus H. Metzeler, Christian Buske, Stefan K. Bohlander, Ulrich Mansmann
Format: Article
Language:English
Published: SAGE Publishing 2008-01-01
Series:Bioinformatics and Biology Insights
Online Access:https://doi.org/10.4137/BBI.S1018