Role of Caveolin 1, E-Cadherin, Enolase 2 and PKCalpha on resistance to methotrexate in human HT29 colon cancer cells

<p>Abstract</p> <p>Background</p> <p>Methotrexate is one of the earliest cytotoxic drugs used in cancer therapy, and despite the isolation of multiple other folate antagonists, methotrexate maintains its significant role as a treatment for different types of cancer and...

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Bibliographic Details
Main Authors: Noé Véronique, Morales Cristina, Selga Elisabet, Peinado Miguel A, Ciudad Carlos J
Format: Article
Language:English
Published: BMC 2008-08-01
Series:BMC Medical Genomics
Online Access:http://www.biomedcentral.com/1755-8794/1/35