Osteoclasts degrade bone and cartilage knee joint compartments through different resorption processes

Osteoclasts degrade bone and cartilage knee joint compartments through different resorption processes

Abstract Background Osteoclasts have been strongly implicated in osteoarthritic cartilage degradation, at least indirectly via bone resorption, and have been shown to degrade cartilage in vitro. The osteoclast resorption processes required to degrade subchondral bone and cartilage—the remodeling of...

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Bibliographic Details
Main Authors: Henrik Löfvall, Hannah Newbould, Morten A. Karsdal, Morten H. Dziegiel, Johan Richter, Kim Henriksen, Christian S. Thudium
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Arthritis Research & Therapy
Subjects:
Osteoarthritis
Osteoclast
Extracellular matrix
Cartilage
Bone
Cell culture
Online Access:http://link.springer.com/article/10.1186/s13075-018-1564-5

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http://link.springer.com/article/10.1186/s13075-018-1564-5

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