TRPC3 Channels in Cardiac Fibrosis

TRPC3 Channels in Cardiac Fibrosis

Cardiac stiffness, caused by interstitial fibrosis due to deposition of extracellular matrix proteins, is thought as a major clinical outcome of heart failure with preserved ejection fraction (HFpEF). Canonical transient receptor potential (TRPC) subfamily proteins are components of Ca2+-permeable n...

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Bibliographic Details
Main Authors: Takuro Numaga-Tomita, Sayaka Oda, Tsukasa Shimauchi, Akiyuki Nishimura, Supachoke Mangmool, Motohiro Nishida
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Ca2+
canonical transient receptor potential
reactive oxygen species
NADPH oxidase
cardiac remodeling
cardiac fibrosis
Online Access:http://journal.frontiersin.org/article/10.3389/fcvm.2017.00056/full

Internet

http://journal.frontiersin.org/article/10.3389/fcvm.2017.00056/full

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