Natural Killer Cell Development and Maturation Revisited: Possible Implications of a Novel Distinct Lin−CD34+DNAM-1brightCXCR4+ Cell Progenitor

Natural Killer Cell Development and Maturation Revisited: Possible Implications of a Novel Distinct Lin−CD34+DNAM-1brightCXCR4+ Cell Progenitor

Since the first description of natural killer (NK) cells, the view on their role in innate immunity has evolved considerably. In addition to first-line defense against transformed and pathogen-infected autologous cells, NK cells contribute to modulate adaptive immune responses and in some cases acqu...

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Bibliographic Details
Main Authors: Federica Bozzano, Francesco Marras, Andrea De Maria
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-03-01
Series:Frontiers in Immunology
Subjects:
natural killer
NK cell development
CD34
DNAM-1
common lymphoid progenitors
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00268/full

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