Thiol trapping and metabolic redistribution of sulfur metabolites enable cells to overcome cysteine overload

Thiol trapping and metabolic redistribution of sulfur metabolites enable cells to overcome cysteine overload

Cysteine is an essential requirement in living organisms. However, due to its reactive thiol side chain, elevated levels of intracellular cysteine can be toxic and therefore need to be rapidly eliminated from the cellular milieu. In mammals and many other organisms, excess cysteine is believed to be...

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Bibliographic Details
Main Authors: Anup Arunrao Deshpande, Amanda Waldner, Sunil Laxman, Anand Kumar Bachhawat
Format: Article
Language:English
Published: Shared Science Publishers OG 2017-03-01
Series:Microbial Cell
Subjects:
cysteine
toxicity
thiol
polyamine
biosynthesis
Saccharomyces cerevisiae
Online Access:http://microbialcell.com/researcharticles/thiol-trapping-and-metabolic-redistribution-of-sulfur-metabolites-enable-cells-to-overcome-cysteine-overload/

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http://microbialcell.com/researcharticles/thiol-trapping-and-metabolic-redistribution-of-sulfur-metabolites-enable-cells-to-overcome-cysteine-overload/

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