A Novel Nuclear Function for the Interleukin-17 Signaling Adaptor Protein Act1.

In the context of the human airway, interleukin-17A (IL-17A) signaling is associated with severe inflammation, as well as protection against pathogenic infection, particularly at mucosal surfaces such as the airway. The intracellular molecule Act1 has been demonstrated to be an essential mediator of...

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Bibliographic Details
Main Authors: Sharlene Velichko, Xu Zhou, Lingxiang Zhu, Johnathon David Anderson, Reen Wu, Yin Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0163323