Antibiotic treatment of severe exacerbations of chronic obstructive pulmonary disease with procalcitonin: a randomized noninferiority trial.

Antibiotic treatment of severe exacerbations of chronic obstructive pulmonary disease with procalcitonin: a randomized noninferiority trial.

The duration of antibiotic treatment of exacerbations of COPD (ECOPD) is controversial. Serum procalcitonin (PCT) is a biomarker of bacterial infection used to identify the cause of ECOPD.We investigated whether a PCT-guided plan would allow a shorter duration of antibiotic treatment in patients wit...

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Main Authors: Alessia Verduri, Fabrizio Luppi, Roberto D'Amico, Sara Balduzzi, Roberto Vicini, Anna Liverani, Valentina Ruggieri, Mario Plebani, Maria Pia Foschino Barbaro, Antonio Spanevello, Giorgio Walter Canonica, Alberto Papi, Leonardo Michele Fabbri, Bianca Beghè, FARM58J2XH Study Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4356612?pdf=render

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