A giant subcutaneous leiomyosarcoma arising in the inguinal region

• Main Authors: Umezu Hajime, Sato Daisuke, Fujita Nobuhiro, Shirai Yoshio, Yajima Kazuhito, Hatakeyama Katsuyoshi
• Format: Article
• Language: English
• Published: BMC 2005-02-01
• Series: World Journal of Surgical Oncology
• Online Access: http://www.wjso.com/content/3/1/14

<p>Abstract</p> <p>Background</p> <p>Subcutaneous leiomyosarcoma is a rare condition that accounts for 1% to 2% of all superficial soft tissue malignancies. Approximately 10% of cases arise in the trunk, although the extremities are the most commonly affected.</p> <p>Case presentation</p> <p>We report herein the case of a 31-year-old man with a subcutaneous leiomyosarcoma, measuring 124 × 105 mm, arising in the left inguinal region. A wide local excision (with a resection margin ≥ 20 mm) was performed. Histological examination of the resected specimen revealed a leiomyosarcoma with high cellularity and two mitoses per 10 high-power fields. The patient remains well with no evidence of disease 5 years and 8 months after the operation.</p> <p>Conclusion</p> <p>This is the first reported case of subcutaneous leiomyosarcoma arising in the inguinal region and also one of the largest tumors reported. The experience of this case and a review of the English-language literature (PubMed, National Library of Medicine, Bethesda, MD, USA) suggest that a resection margin of ≥ 10 mm is recommended when excising this rare tumor.</p>