Carbon monoxide promotes respiratory hemoproteins iron reduction using peroxides as electron donors.

The physiological role of the respiratory hemoproteins (RH), hemoglobin and myoglobin, is to deliver O(2) via its binding to their ferrous (Fe(II)) heme-iron. Under variety of pathological conditions RH proteins leak to blood plasma and oxidized to ferric (Fe(III), met) forms becoming the source of...

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Bibliographic Details
Main Authors: Elena A Sher, Mati Shaklai, Nurith Shaklai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3299724?pdf=render