Hepatitis B virus particles activate B cells through the TLR2–MyD88–mTOR axis

Abstract Host immune control plays a pivotal role in resolving primary hepatitis-B-virus (HBV) infections. The complex interaction between HBV and host immune cells, however, remains unclear. In this study, the transcriptional profiling of specimens from animals infected with woodchuck hepatitis vir...

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Bibliographic Details
Main Authors: Qian Li, Jun Wang, Heba Islam, Carsten Kirschning, Hongzhou Lu, Daniel Hoffmann, Ulf Dittmer, Mengji Lu
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-020-03284-1