Matrix metalloproteinase 9 production by monocytes is enhanced by TNF and participates in the pathology of human cutaneous Leishmaniasis.

Matrix metalloproteinase 9 production by monocytes is enhanced by TNF and participates in the pathology of human cutaneous Leishmaniasis.

INTRODUCTION:Cutaneous leishmaniasis (CL) due to L.braziliensis infection is characterized by a strong inflammatory response with high levels of TNF and ulcer development. Less attention has been given to the role of mononuclear phagocytes to this process. Monocytes constitute a heterogeneous popula...

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Bibliographic Details
Main Authors: Taís M Campos, Sara T Passos, Fernanda O Novais, Daniel P Beiting, Rúbia S Costa, Adriano Queiroz, David Mosser, Phillip Scott, Edgar M Carvalho, Lucas P Carvalho
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4230914?pdf=render

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