HIV infection of non-dividing cells: a divisive problem

<p>Abstract</p> <p>Understanding how lentiviruses can infect terminally differentiated, non-dividing cells has proven a very complex and controversial problem. It is, however, a problem worth investigating, for it is central to HIV-1 transmission and AIDS pathogenesis. Here I shall...

Full description

Bibliographic Details
Main Author: Fassati Ariberto
Format: Article
Language:English
Published: BMC 2006-10-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/3/1/74
Description
Summary:<p>Abstract</p> <p>Understanding how lentiviruses can infect terminally differentiated, non-dividing cells has proven a very complex and controversial problem. It is, however, a problem worth investigating, for it is central to HIV-1 transmission and AIDS pathogenesis. Here I shall attempt to summarise what is our current understanding for HIV-1 infection of non-dividing cells. In some cases I shall also attempt to make sense of controversies in the field and advance one or two modest proposals.</p>
ISSN:1742-4690