Identification and enhancement of HLA-A2.1-restricted CTL epitopes in a new human cancer antigen-POTE.

Identification of CD8(+) T cell epitopes that can induce T cells to kill tumor cells is a fundamental step for development of a peptide cancer vaccine. POTE protein is a newly identified cancer antigen that was found to be expressed in a wide variety of human cancers, including prostate, colon, lung...

Full description

Bibliographic Details
Main Authors: Yi-Hsiang Huang, Masaki Terabe, C David Pendleton, Deborah Stewart Khursigara, Tapan K Bera, Ira Pastan, Jay A Berzofsky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3672105?pdf=render