New Structure Sheds Light on Selective HIV-1 Genomic RNA Packaging

New Structure Sheds Light on Selective HIV-1 Genomic RNA Packaging

Two copies of unspliced human immunodeficiency virus (HIV)-1 genomic RNA (gRNA) are preferentially selected for packaging by the group-specific antigen (Gag) polyprotein into progeny virions as a dimer during the late stages of the viral lifecycle. Elucidating the RNA features responsible for select...

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Bibliographic Details
Main Authors: Erik D. Olson, William A. Cantara, Karin Musier-Forsyth
Format: Article
Language:English
Published: MDPI AG 2015-08-01
Series:Viruses
Subjects:
HIV
RNA structure
retroviral packaging
NMR
psi
Online Access:http://www.mdpi.com/1999-4915/7/8/2846

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