Systems modeling predicts that mitochondria ER contact sites regulate the postsynaptic energy landscape
Abstract Spatiotemporal compartmentation of calcium dynamics is critical for neuronal function, particularly in postsynaptic spines. This exquisite level of Ca2+ compartmentalization is achieved through the storage and release of Ca2+ from various intracellular organelles particularly the endoplasmi...
Main Authors: | A. Leung, D. Ohadi, G. Pekkurnaz, P. Rangamani |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-06-01
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Series: | npj Systems Biology and Applications |
Online Access: | https://doi.org/10.1038/s41540-021-00185-7 |
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