A Case of Neonatal Neutropenia Due to Anti-Fc Gamma Receptor IIIb Isoantibodies Treated with Recombinant Human Granulocyte Colony Stimulating Factor

Alloimmunization to granulocyte-specific antigens can occur during pregnancy. Maternal antibodies of IgG class can cross the placenta to result in alloimmune neonatal neutropenia. Antibodies to human neutrophil antigens anti-HNA-1a, HNA-1b, and HNA-2a have been most commonly reported to cause alloim...

Full description

Bibliographic Details
Main Authors: Maja Tomicic, Mirta Starcevic, Vanja Zach, Jasna Bingulac-Popovic, Zeljka Hundric-Haspl
Format: Article
Language:English
Published: Hindawi Limited 2009-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2009/717545