PD-L1 regulation by SDH5 via β-catenin/ZEB1 signaling

PD-L1 regulation by SDH5 via β-catenin/ZEB1 signaling

Programmed death-ligand 1 (PD-L1) is a crucial target for lung cancer immunotherapy. In lung cancer patients with high PD-L1 expression, blocking or reducing its expression can inhibit tumor growth. PD-L1 is regulated by signaling pathways, transcription factors and epigenetic factors, such as the G...

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Bibliographic Details
Main Authors: Zhan Tuo, Yan Zong, Jie Li, Guangqin Xiao, Furong Zhang, Guiling Li, Sihua Wang, Yi Lv, Jiahong Xia, Jun Liu
Format: Article
Language:English
Published: Taylor & Francis Group 2019-12-01
Series:OncoImmunology
Subjects:
lung cancer
pd-l1
sdh5
emt
immunotherapy
Online Access:http://dx.doi.org/10.1080/2162402X.2019.1655361

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