Two simple and rapid methods based on maximum diameter accurately estimate large lesion volumes in acute stroke

Two simple and rapid methods based on maximum diameter accurately estimate large lesion volumes in acute stroke

Abstract Background We compared two simple and rapid diameter‐based methods (ABC/2, od‐value) in terms of their accuracy in predicting lesion volume >70 ml and >100 ml. Methods In 238 DWI images of ischemic stroke patients from the AXIS2 trial, maximum lesion diameter and corresponding maximum...

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Main Authors: Anna Kufner, Jonas Stief, Bob Siegerink, Christian Nolte, Matthias Endres, Jochen B. Fiebach
Format: Article
Language:English
Published: Wiley 2020-11-01
Series:Brain and Behavior
Subjects:
diffusion‐weighted imaging
magnetic resonance imaging
stroke
Online Access:https://doi.org/10.1002/brb3.1828
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spelling doaj-e27ac97b12534572b7acdaf4750875682020-11-25T04:03:44ZengWileyBrain and Behavior2162-32792020-11-011011n/an/a10.1002/brb3.1828Two simple and rapid methods based on maximum diameter accurately estimate large lesion volumes in acute strokeAnna Kufner0Jonas Stief1Bob Siegerink2Christian Nolte3Matthias Endres4Jochen B. Fiebach5Department of Neurology Center for Stroke Research Berlin (CSB) Charité – Universitätsmedizin Berlin GermanyDepartment of Radiology Charité – Universitätsmedizin Berlin GermanyDepartment of Neurology Center for Stroke Research Berlin (CSB) Charité – Universitätsmedizin Berlin GermanyDepartment of Neurology Center for Stroke Research Berlin (CSB) Charité – Universitätsmedizin Berlin GermanyDepartment of Neurology Center for Stroke Research Berlin (CSB) Charité – Universitätsmedizin Berlin GermanyDepartment of Neurology Center for Stroke Research Berlin (CSB) Charité – Universitätsmedizin Berlin GermanyAbstract Background We compared two simple and rapid diameter‐based methods (ABC/2, od‐value) in terms of their accuracy in predicting lesion volume >70 ml and >100 ml. Methods In 238 DWI images of ischemic stroke patients from the AXIS2 trial, maximum lesion diameter and corresponding maximum orthogonal diameter were measured. Estimation of infarct volume based on od‐value and ABC/2 calculation was compared to volumetric assessments. Results Accuracy of od‐value and ABC/2 was similar for >70 ml (92.0 vs. 87.4) and >100 ml (92.9 vs. 93.3). ABC/2 overestimated lesion volume by 29.9%, resulting in a lower specificity. Conclusions Od‐value is a robust tool for patient selection in trials.https://doi.org/10.1002/brb3.1828diffusion‐weighted imagingmagnetic resonance imagingstroke
collection DOAJ
language English
format Article
sources DOAJ
author Anna Kufner
Jonas Stief
Bob Siegerink
Christian Nolte
Matthias Endres
Jochen B. Fiebach
spellingShingle Anna Kufner
Jonas Stief
Bob Siegerink
Christian Nolte
Matthias Endres
Jochen B. Fiebach
Two simple and rapid methods based on maximum diameter accurately estimate large lesion volumes in acute stroke
Brain and Behavior
diffusion‐weighted imaging
magnetic resonance imaging
stroke
author_facet Anna Kufner
Jonas Stief
Bob Siegerink
Christian Nolte
Matthias Endres
Jochen B. Fiebach
author_sort Anna Kufner
title Two simple and rapid methods based on maximum diameter accurately estimate large lesion volumes in acute stroke
title_short Two simple and rapid methods based on maximum diameter accurately estimate large lesion volumes in acute stroke
title_full Two simple and rapid methods based on maximum diameter accurately estimate large lesion volumes in acute stroke
title_fullStr Two simple and rapid methods based on maximum diameter accurately estimate large lesion volumes in acute stroke
title_full_unstemmed Two simple and rapid methods based on maximum diameter accurately estimate large lesion volumes in acute stroke
title_sort two simple and rapid methods based on maximum diameter accurately estimate large lesion volumes in acute stroke
publisher Wiley
series Brain and Behavior
issn 2162-3279
publishDate 2020-11-01
description Abstract Background We compared two simple and rapid diameter‐based methods (ABC/2, od‐value) in terms of their accuracy in predicting lesion volume >70 ml and >100 ml. Methods In 238 DWI images of ischemic stroke patients from the AXIS2 trial, maximum lesion diameter and corresponding maximum orthogonal diameter were measured. Estimation of infarct volume based on od‐value and ABC/2 calculation was compared to volumetric assessments. Results Accuracy of od‐value and ABC/2 was similar for >70 ml (92.0 vs. 87.4) and >100 ml (92.9 vs. 93.3). ABC/2 overestimated lesion volume by 29.9%, resulting in a lower specificity. Conclusions Od‐value is a robust tool for patient selection in trials.
topic diffusion‐weighted imaging
magnetic resonance imaging
stroke
url https://doi.org/10.1002/brb3.1828
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