Two simple and rapid methods based on maximum diameter accurately estimate large lesion volumes in acute stroke

Two simple and rapid methods based on maximum diameter accurately estimate large lesion volumes in acute stroke

Abstract Background We compared two simple and rapid diameter‐based methods (ABC/2, od‐value) in terms of their accuracy in predicting lesion volume >70 ml and >100 ml. Methods In 238 DWI images of ischemic stroke patients from the AXIS2 trial, maximum lesion diameter and corresponding maximum...

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Bibliographic Details
Main Authors: Anna Kufner, Jonas Stief, Bob Siegerink, Christian Nolte, Matthias Endres, Jochen B. Fiebach
Format: Article
Language:English
Published: Wiley 2020-11-01
Series:Brain and Behavior
Subjects:
diffusion‐weighted imaging
magnetic resonance imaging
stroke
Online Access:https://doi.org/10.1002/brb3.1828
Description
Summary:Abstract Background We compared two simple and rapid diameter‐based methods (ABC/2, od‐value) in terms of their accuracy in predicting lesion volume >70 ml and >100 ml. Methods In 238 DWI images of ischemic stroke patients from the AXIS2 trial, maximum lesion diameter and corresponding maximum orthogonal diameter were measured. Estimation of infarct volume based on od‐value and ABC/2 calculation was compared to volumetric assessments. Results Accuracy of od‐value and ABC/2 was similar for >70 ml (92.0 vs. 87.4) and >100 ml (92.9 vs. 93.3). ABC/2 overestimated lesion volume by 29.9%, resulting in a lower specificity. Conclusions Od‐value is a robust tool for patient selection in trials.
ISSN:2162-3279

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