From the Gut to the Liver: Another Organ to Watch in FAP Patients

From the Gut to the Liver: Another Organ to Watch in FAP Patients

We report a rare association of hepatocellular carcinoma with familial adenomatous polyposis in a young patient and its clinical significance. A 28-year-old female with a past medical history of familial adenomatous polyposis (FAP) and subsequent colonic adenocarcinoma underwent total colectomy. She...

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Main Authors: Spencer Paulson, Charmi Patel, Hitendra Patel
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Case Reports in Pathology
Online Access:http://dx.doi.org/10.1155/2016/1738696
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spelling doaj-e26bff43c3db4fdb91bf5d85dbca39a62020-11-24T22:51:21ZengHindawi LimitedCase Reports in Pathology2090-67812090-679X2016-01-01201610.1155/2016/17386961738696From the Gut to the Liver: Another Organ to Watch in FAP PatientsSpencer Paulson0Charmi Patel1Hitendra Patel2Department of Pathology, University of Arizona, Tucson, AZ 85724, USADepartment of Pathology, University of Arizona, Tucson, AZ 85724, USASection of Hematology and Oncology, University of Arizona, Tucson, AZ 85724, USAWe report a rare association of hepatocellular carcinoma with familial adenomatous polyposis in a young patient and its clinical significance. A 28-year-old female with a past medical history of familial adenomatous polyposis (FAP) and subsequent colonic adenocarcinoma underwent total colectomy. She later presented with intermittent right upper quadrant pain and nausea of four months’ duration. MRI of the abdomen revealed multiple liver lesions, the largest 8.5 cm in diameter, with radiologic features suggestive of hepatocellular carcinoma. A CT-guided liver biopsy demonstrated well-differentiated HCC which was confirmed by immunohistochemistry. In patients with a history of FAP, a heightened awareness of the possibility of concurrent or subsequent HCC is warranted.http://dx.doi.org/10.1155/2016/1738696
collection DOAJ
language English
format Article
sources DOAJ
author Spencer Paulson
Charmi Patel
Hitendra Patel
spellingShingle Spencer Paulson
Charmi Patel
Hitendra Patel
From the Gut to the Liver: Another Organ to Watch in FAP Patients
Case Reports in Pathology
author_facet Spencer Paulson
Charmi Patel
Hitendra Patel
author_sort Spencer Paulson
title From the Gut to the Liver: Another Organ to Watch in FAP Patients
title_short From the Gut to the Liver: Another Organ to Watch in FAP Patients
title_full From the Gut to the Liver: Another Organ to Watch in FAP Patients
title_fullStr From the Gut to the Liver: Another Organ to Watch in FAP Patients
title_full_unstemmed From the Gut to the Liver: Another Organ to Watch in FAP Patients
title_sort from the gut to the liver: another organ to watch in fap patients
publisher Hindawi Limited
series Case Reports in Pathology
issn 2090-6781
2090-679X
publishDate 2016-01-01
description We report a rare association of hepatocellular carcinoma with familial adenomatous polyposis in a young patient and its clinical significance. A 28-year-old female with a past medical history of familial adenomatous polyposis (FAP) and subsequent colonic adenocarcinoma underwent total colectomy. She later presented with intermittent right upper quadrant pain and nausea of four months’ duration. MRI of the abdomen revealed multiple liver lesions, the largest 8.5 cm in diameter, with radiologic features suggestive of hepatocellular carcinoma. A CT-guided liver biopsy demonstrated well-differentiated HCC which was confirmed by immunohistochemistry. In patients with a history of FAP, a heightened awareness of the possibility of concurrent or subsequent HCC is warranted.
url http://dx.doi.org/10.1155/2016/1738696
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AT charmipatel fromtheguttotheliveranotherorgantowatchinfappatients
AT hitendrapatel fromtheguttotheliveranotherorgantowatchinfappatients
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